I have been taking these vitamins for 10 years now, I think? Sorry my memory when I was 21 is hazy. But they work fantastically. I push them onto my friends and family and they all come back saying the same thing. I take a lot of pride and care in my health, but I also drink consistently (and responsibly) so these are a staple in my life and I recommend anyone who can relate to the lifestyle that I just described to join the movement.